Table 2 Combined pre- and postmenopausal breast cancer
From: Meat consumption and risk of breast cancer in the UK Women's Cohort Study
Model 1 a | Model 2 b | ||||||
|---|---|---|---|---|---|---|---|
Consumption ( g /day) | Person years (mean (s.d.)) | Cases/non-cases | HR | 95% CI | HR | 95% CI | |
Total meat | |||||||
Categorical | |||||||
None (ref) | 0 | 7.50 (0.68) | 149/8881 | 1.00 | — | 1.00 | — |
Low | <62 | 7.25 (0.92) | 162/8281 | 1.10 | (0.88, 1.39) | 1.04 | (0.82, 1.33) |
Medium | 62–103 | 6.79 (0.98) | 182/8282 | 1.30 | (1.04, 1.63) | 1.25 | (0.98, 1.60) |
High | >103 | 6.63 (0.94) | 185/8281 | 1.40 | (1.12, 1.75) | 1.34 | (1.05, 1.71) |
Continuous | Risk per 50 g/day | 1.11 | (1.05, 1.17) | 1.11 | (1.04, 1.18) | ||
P (trend) <0.001 | P (trend)=0.001 | ||||||
Test for effect modification by menopausal status | 0.0269 | 0.0492 | |||||
Non-processed meat (including red meat, poultry and offal) | |||||||
Categorical | |||||||
None (ref) | 0 | 7.51 (0.67) | 151/9135 | 1.00 | — | 1.00 | — |
Low | <50 | 7.22 (0.93) | 163/8196 | 1.12 | (0.89, 1.41) | 1.07 | (0.84, 1.36) |
Medium | 50–84 | 6.79 (0.98) | 185/8198 | 1.34 | (1.07, 1.68) | 1.34 | (1.05, 1.70) |
High | >84 | 6.63 (0.94) | 179/8196 | 1.37 | (1.09, 1.72) | 1.33 | (1.04, 1.69) |
Continuous | Risk per 50 g/day | 1.11 | (1.04, 1.18) | 1.10 | (1.03, 1.19) | ||
P (trend)=0.003 | P (trend)=0.007 | ||||||
Test for effect modification by menopausal status | 0.0454 | 0.0452 | |||||
Processed meat | |||||||
Categorical | |||||||
None (ref) | 0 | 7.51 (0.70) | 175/10306 | 1.00 | — | 1.00 | — |
Low | <10 | 7.08 (0.94) | 160/7824 | 1.17 | (0.93, 1.47) | 1.19 | (0.94, 1.53) |
Medium | 10–20 | 6.77 (0.99) | 172/7814 | 1.31 | (1.04, 1.64) | 1.30 | (1.02, 1.66) |
High | >20 | 6.69 (0.95) | 171/7781 | 1.35 | (1.08, 1.70) | 1.39 | (1.09, 1.78) |
Continuous | Risk per 50 g/day | 1.40 | (1.18, 1.67) | 1.59 | (1.22, 2.06) | ||
P (trend) <0.001 | P (trend) <0.001 | ||||||
Test for effect modification by menopausal status | 0.1365 | 0.4523 | |||||
Red meat | |||||||
Categorical | |||||||
None (ref) | 0 | 7.52 (0.68) | 186/11199 | 1.00 | — | 1.00 | — |
Low | <32 | 7.15 (0.97) | 162/7512 | 1.28 | (1.02, 1.61) | 1.21 | (0.95, 1.54) |
Medium | 32–57 | 6.72 (0.95) | 163/7560 | 1.36 | (1.08, 1.71) | 1.40 | (1.10, 1.78) |
High | >57 | 6.57 (0.93) | 167/7454 | 1.47 | (1.17, 1.84) | 1.41 | (1.11, 1.81) |
Continuous | Risk per 50 g/day | 1.12 | (1.03, 1.21) | 1.12 | (1.03, 1.22) | ||
P (trend)=0.005 | P (trend)=0.007 | ||||||
Test for effect modification by menopausal status | 0.0325 | 0.0577 | |||||
Poultry | |||||||
Categorical | |||||||
None (ref) | 0 | 7.48 (0.70) | 160/9607 | 1.00 | — | 1.00 | — |
Low | <14 | 6.96 (0.98) | 160/7401 | 1.24 | (0.97, 1.57) | 1.19 | (0.92, 1.54) |
Medium | 14–23 | 6.81 (0.99) | 191/8678 | 1.30 | (1.03, 1.63) | 1.25 | (0.98, 1.59) |
High | >23 | 6.88 (0.97) | 167/8039 | 1.25 | (0.99, 1.58) | 1.22 | (0.95, 1.56) |
Continuous | Risk per 50 g/day | 1.14 | (0.95, 1.35) | 1.11 | (0.92, 1.34) | ||
P (trend)=0.154 | P (trend)=0.285 | ||||||
Test for effect modification by menopausal status | 0.7242 | 0.8897 | |||||
Offal | |||||||
Categorical | |||||||
None (ref) | 0 | 7.23 (0.88) | 366/20499 | 1.00 | — | 1.00 | — |
Low | ⩽2 | 6.79 (0.99) | 190/7833 | 1.34 | (1.11, 1.61) | 1.35 | (1.11, 1.64) |
— | — | — | — | — | — | ||
High | >2 | 6.73 (0.99) | 122/5393 | 1.22 | (0.99, 1.52) | 1.17 | (0.93, 1.48) |
Continuous | Risk per 50 g/day | 1.92 | (0.81, 4.53) | 1.75 | (0.68, 4.50) | ||
P (trend)=0.136 | P (trend)=0.248 | ||||||
Test for effect modification by menopausal status | 0.6334 | 0.6039 | |||||
