Table 1 HrHPV type-specific prevalence rates in high-grade cervical intraepithelial neoplasia vs squamous cell carcinoma

From: The contribution of HPV18 to cervical cancer is underestimated using high-grade CIN as a measure of screening efficiency

 

All infections a ,b

Single infections a

 

SCC

CIN2/3

SCC>CIN2/3

 

SCC

CIN2/3

SCC>CIN2/3

 
 

n =84

n =139

  

n =74

n =126

  

Type

N (%)

N (%)

OR (95% CI)

P

N (%)

N (%)

OR (95% CI)

P

16

58 (69.9)

83 (59.7)

1.5 (0.8–3.1)

0.229

55 (74.3)

75 (59.5)

2.1 (1.0–4.5)

0.065

18

10 (12.0)

4 (2.9)

8.3 (1.9–36)

0.002

8 (10.8)

3 (2.4)

10 (2.0–52)

0.005

n16/n18

17 (20.5)

51 (36.7)

0.4 (0.2–0.8)

0.009

11 (14.9)

47 (37.3)

0.2 (0.1–0.5)

0.001

31

6 (7.2)

18 (12.9)

0.4 (0.1–1.5)

0.145

3 (4.1)

11 (8.7)

0.5 (0.1–2.1)

0.371

33

3 (3.6)

8 (5.8)

1.0 (0.2–4.6)

0.959

1 (1.4)

7 (5.6)

0.4 (0.1–3.4)

0.390

35

2 (2.4)

5 (3.6)

0.2 (0.1–3.3)

0.272

3 (2.4)

39

4 (4.8)

1 (1.4)

45

5 (6.0)

6 (4.3)

0.8 (0.1–6.1)

0.850

4 (5.4)

3 (2.4)

0.6 (0.1–8.1)

0.701

51

4 (2.9)

3 (2.4)

52

16 (11.5)

14 (11.1)

56

2 (2.4)

1 (0.7)

1.6 (0.1–46)

0.815

1 (1.4)

1 (0.8)

1.7 (0.1–28)

0.705

58

2 (2.4)

7 (5.0)

1.6 (0.1–11)

0.652

1 (1.4)

4 (3.2)

0.6 (0.1–9.0)

0.738

59

1 (0.7)

1 (0.8)

66

1 (0.7)

68

  1. CIN2/3=cervical intraepithelial neoplasia; HrHPV=high-risk human papillomavirus; SCC, squamous cell carcinoma.
  2. Bold typeface indicates P<0.05.
  3. aAnalyses are adjusted for age in 5-year strata.
  4. bMultiple and single infections combined. Analyses are adjusted for multiplicity of infection.