Table 1 Risks for gastric cancer in offspring by familial cancers (1961–2004)

From: Familial risk for gastric carcinoma: an updated study from Sweden

 

Parently only

Sibling only

Parent and sibling

Familial cancer sites

O

SIR

95%CI

O

SIR

95%CI

O

SIR

95%CI

Upper aerodigestive tract

37

1.09

0.77

1.51

10

1.14

0.54

2.11

0

   

Oesophagus

14

1.14

0.62

1.92

5

1.95

0.61

4.58

0

   

Stomach

133

1.63

1.36

1.93

20

2.93

1.79

4.53

2

4.93

0.46

18.13

Adenocarcinoma

116

1.63

1.34

1.95

18

2.90

1.71

4.59

2

6.02

0.57

22.13

Colorectum

182

1.04

0.90

1.21

41

1.37

0.99

1.87

4

1.17

0.30

3.03

Liver

55

1.12

0.85

1.46

4

0.70

0.18

1.82

0

   

Pancreas

49

1.03

0.76

1.36

9

1.41

0.64

2.69

0

   

Lung

112

1.10

0.90

1.32

32

1.34

0.92

1.90

6

4.19

1.51

9.19

Breast

150

1.04

0.88

1.22

84

1.10

0.88

1.36

3

0.49

0.09

1.45

Cervix

31

1.06

0.72

1.50

12

1.17

0.60

2.04

0

   

Endometrium

41

1.08

0.77

1.47

21

1.65

1.02

2.53

1

2.92

0.00

16.75

Ovary

42

1.25

0.90

1.69

20

1.58

0.97

2.45

0

   

Other female genital

8

1.12

0.48

2.21

0

   

0

   

Prostate

207

1.00

0.87

1.15

40

1.11

0.79

1.51

5

0.83

0.26

1.96

Other male genital

7

2.76

1.09

5.72

2

2.11

0.20

7.75

0

   

Kidney

50

1.04

0.77

1.37

10

1.01

0.48

1.86

0

   

Urinay bladder

71

1.03

0.80

1.30

24

1.67

1.07

2.49

3

4.98

0.94

14.73

Melanoma

25

0.90

0.58

1.33

26

1.18

0.77

1.74

0

   

Skin

51

0.91

0.67

1.19

11

1.38

0.69

2.48

0

   

Nervous system

33

0.92

0.63

1.29

25

1.32

0.85

1.95

0

   

Thyroid gland

10

0.96

0.46

1.78

9

1.55

0.70

2.96

0

   

Endocrine glands

12

0.55

0.28

0.97

16

1.55

0.88

2.52

0

   

Connective tissue

13

1.45

0.77

2.49

6

1.87

0.67

4.10

0

   

Non-Hodgkin's lymphoma

49

1.25

0.92

1.65

19

1.34

0.80

2.09

0

   

Hodgkin's disease

8

1.23

0.53

2.44

2

0.63

0.06

2.30

0

   

Myeloma

24

1.02

0.65

1.51

2

0.50

0.05

1.83

0

   

Leukemia

35

0.85

0.59

1.18

10

1.03

0.49

1.90

0

   

All

1104

1.04

0.98

1.10

231

1.18

1.04

1.35

205

1.26

1.09

1.44

  1. CI=confidence interval, O, observed cases. Bold type: 95%CI does not include 1.00; underline type, 99%CI does not include 1.00.