Table 1 Risks for gastric cancer in offspring by familial cancers (1961–2004)
From: Familial risk for gastric carcinoma: an updated study from Sweden
Parently only | Sibling only | Parent and sibling | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Familial cancer sites | O | SIR | 95%CI | O | SIR | 95%CI | O | SIR | 95%CI | |||
Upper aerodigestive tract | 37 | 1.09 | 0.77 | 1.51 | 10 | 1.14 | 0.54 | 2.11 | 0 | |||
Oesophagus | 14 | 1.14 | 0.62 | 1.92 | 5 | 1.95 | 0.61 | 4.58 | 0 | |||
Stomach | 133 | 1.63 | 1.36 | 1.93 | 20 | 2.93 | 1.79 | 4.53 | 2 | 4.93 | 0.46 | 18.13 |
Adenocarcinoma | 116 | 1.63 | 1.34 | 1.95 | 18 | 2.90 | 1.71 | 4.59 | 2 | 6.02 | 0.57 | 22.13 |
Colorectum | 182 | 1.04 | 0.90 | 1.21 | 41 | 1.37 | 0.99 | 1.87 | 4 | 1.17 | 0.30 | 3.03 |
Liver | 55 | 1.12 | 0.85 | 1.46 | 4 | 0.70 | 0.18 | 1.82 | 0 | |||
Pancreas | 49 | 1.03 | 0.76 | 1.36 | 9 | 1.41 | 0.64 | 2.69 | 0 | |||
Lung | 112 | 1.10 | 0.90 | 1.32 | 32 | 1.34 | 0.92 | 1.90 | 6 | 4.19 | 1.51 | 9.19 |
Breast | 150 | 1.04 | 0.88 | 1.22 | 84 | 1.10 | 0.88 | 1.36 | 3 | 0.49 | 0.09 | 1.45 |
Cervix | 31 | 1.06 | 0.72 | 1.50 | 12 | 1.17 | 0.60 | 2.04 | 0 | |||
Endometrium | 41 | 1.08 | 0.77 | 1.47 | 21 | 1.65 | 1.02 | 2.53 | 1 | 2.92 | 0.00 | 16.75 |
Ovary | 42 | 1.25 | 0.90 | 1.69 | 20 | 1.58 | 0.97 | 2.45 | 0 | |||
Other female genital | 8 | 1.12 | 0.48 | 2.21 | 0 | 0 | ||||||
Prostate | 207 | 1.00 | 0.87 | 1.15 | 40 | 1.11 | 0.79 | 1.51 | 5 | 0.83 | 0.26 | 1.96 |
Other male genital | 7 | 2.76 | 1.09 | 5.72 | 2 | 2.11 | 0.20 | 7.75 | 0 | |||
Kidney | 50 | 1.04 | 0.77 | 1.37 | 10 | 1.01 | 0.48 | 1.86 | 0 | |||
Urinay bladder | 71 | 1.03 | 0.80 | 1.30 | 24 | 1.67 | 1.07 | 2.49 | 3 | 4.98 | 0.94 | 14.73 |
Melanoma | 25 | 0.90 | 0.58 | 1.33 | 26 | 1.18 | 0.77 | 1.74 | 0 | |||
Skin | 51 | 0.91 | 0.67 | 1.19 | 11 | 1.38 | 0.69 | 2.48 | 0 | |||
Nervous system | 33 | 0.92 | 0.63 | 1.29 | 25 | 1.32 | 0.85 | 1.95 | 0 | |||
Thyroid gland | 10 | 0.96 | 0.46 | 1.78 | 9 | 1.55 | 0.70 | 2.96 | 0 | |||
Endocrine glands | 12 | 0.55 | 0.28 | 0.97 | 16 | 1.55 | 0.88 | 2.52 | 0 | |||
Connective tissue | 13 | 1.45 | 0.77 | 2.49 | 6 | 1.87 | 0.67 | 4.10 | 0 | |||
Non-Hodgkin's lymphoma | 49 | 1.25 | 0.92 | 1.65 | 19 | 1.34 | 0.80 | 2.09 | 0 | |||
Hodgkin's disease | 8 | 1.23 | 0.53 | 2.44 | 2 | 0.63 | 0.06 | 2.30 | 0 | |||
Myeloma | 24 | 1.02 | 0.65 | 1.51 | 2 | 0.50 | 0.05 | 1.83 | 0 | |||
Leukemia | 35 | 0.85 | 0.59 | 1.18 | 10 | 1.03 | 0.49 | 1.90 | 0 | |||
All | 1104 | 1.04 | 0.98 | 1.10 | 231 | 1.18 | 1.04 | 1.35 | 205 | 1.26 | 1.09 | 1.44 |