Table 4 Multivariate analysis of clinicopathological and genetic parameters for DFS (Cox regression hazard analysis)

From: Studies on p53, BAX and Bcl-2 protein expression and microsatellite instability in stage III (UICC) colon cancer treated by adjuvant chemotherapy: major prognostic impact of proapoptotic BAX

 

DFS

Prognostic factor

P -values

Hazard ratio

95% CI

Step 1

pT category

 T3/4

0.11

2.6

0.8–8.3

pN category

 N2/3

0.008

1.9

1.2–3.1

Differentiation

 G3/4

0.22

1.4

0.8–2.3

Treatment arm

 Arm B (5-FU/LEV)

0.01

1.9

1.2–3.0

BSI

 Low

0.001

2.2

1.4–3.6

Step 2

   

pT category

 T3/T4

0.09

2.7

0.9–8.7

pN category

 N2/3

0.005

2

1.2–3.2

BSI

 Low

0.001

2.3

1.4–3.7

Treatment arm

 Arm B (5-FU/LEV)

0.008

1.9

1.2–3.1

  1. CI=confidence interval; DFS=disease-free survival; 5-FU=5-fluorouracil; LEV=levamisole. Bold values signify P<0.05.
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