Table 5 Main results from the recent gene expression signatures in breast cancer

70-gene signature

Cell cycle, angiogenesis, invasion and metastasis

van't Veer et al (2002)

76-gene signature

Cell cycle, proliferation, DNA repair, immune response and apoptosis

Wang et al (2005)

Recurrence score

Proliferation, estrogen receptor and Her2 status, invasion and 5 reference genes

Paik et al (2004)

Genomic grade index

Cell cycle and proliferation genes

Sotiriou et al (2006)

p53-signature

Proliferation genes and transcription factors (not p53 targets)

Miller et al (2005)

Death from cancer signature

Cell cycle and proliferation genes

Glinsky et al (2005)

Estrogen-regulated gene expression signature

Proliferation and antiapoptosis genes

Oh et al (2006)