Table 3 Deterministic mean utility scores used in the model (n=23)

From: Cost-effectiveness analysis of anastrozole vs tamoxifen in adjuvant therapy for early stage breast cancer in the United Kingdom: the 5-year completed treatment analysis of the ATAC (‘Arimidex’, Tamoxifen alone or in combination) trial

  

Probabilistic parameters

Utility item

Mean (s.d.)

α

β

Disease-free state, no adverse events

0.989 (0.010)

106.60

1.19

Common adverse events (tamoxifen)

0.970 (0.041)

15.82

0.49

Common adverse events (anastrozole)

0.962 (0.055)

10.66

0.42

Vaginal bleeding

0.933 (0.099)

5.02

0.36

Endometrial cancer

0.913 (0.101)

6.20

0.59

Wrist fracture

0.916 (0.099)

6.28

0.58

New contralateral breast cancer

0.914 (0.097)

6.72

0.63

Local/regional recurrence

0.911 (0.098)

6.78

0.66

Deep vein thromboembolism

0.922 (0.107)

4.87

0.41

Pulmonary embolism

0.890 (0.166)

2.27

0.28

Spinal fracture

0.894 (0.189)

1.48

0.18

Hip fracture

0.858 (0.199)

1.78

0.29

Hormonal therapy for distant recurrence

0.882 (0.105)

7.44

1.00

Chemotherapy for distant recurrence

0.710 (0.254)

1.56

0.64

Current health

0.933 (0.069)

11.32

0.81

Hysterectomy

0.899 (0.101)

7.10

0.80