Table 5 Sensitivity of the incremental cost/QALY ratio to parameters

From: Cost-effectiveness analysis of anastrozole vs tamoxifen in adjuvant therapy for early stage breast cancer in the United Kingdom: the 5-year completed treatment analysis of the ATAC (‘Arimidex’, Tamoxifen alone or in combination) trial

Parameter

Contribution of parameters to the variability of the ICER (%)

Rank correlation

Weibull regression parameter (α coefficient)a

63.0

−0.85

Weibull regression parameter (constant)a

14.2

0.40

Cost of bisphosphonate treatment

5.5

0.25

Probability of receiving bisphosphonate treatment

3.3

0.19

Proportion of patients with a distant recurrence if relapsing

1.5

0.13

Utility of chemotherapy for distant cancer

1.9

0.15

  1. Abbreviations: ICER=incremental cost effectiveness ratio; QALY=quality-adjusted life year.
  2. aCorrelated parameter.
Back to article page