Figure 4 | British Journal of Cancer

Figure 4

From: Human DESC1 serine protease confers tumorigenic properties to MDCK cells and it is upregulated in tumours of different origin

Figure 4

(A) HGF-stimulated MDCK/DESC1 cells embebbed in collagen gel form tubular structures. MDCK cell clones stably transfected with control vector or expressing DESC1 were cultured in a type I collagen matrix for 7 days in presence (+) or in absence (−) of 30 ng ml−1 of HGF, and in the presence (+) or absence (−) of 50 μ M of AEBSF. The branching extensions formed by MDCK/DESC1 cells are indicated by arrows. (B) Quantification of the number and length of tubular structures of 15 randomly selected microscopic fields following HGF stimulation.

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