Table 3 The distribution of F-cells detected immunohistochemically in retinoblastoma patients

From: Foetal haemoglobin-blood cells (F-cells) as a feature of embryonic tumours (blastomas)

No

Gender

Age (years)

F-cells features (1) Checked in tumour tissues

Staining grade

1

Male

1

In BV, 50–100% Fc, 20–50% of them Feb. Proliferation of such BV and of free Fer,Feb clusters.

Congestions of Fc in haemorrhagic regions. Some Feb in mitosis, or as binucleated.

(+++)

2

Male

1

Same as above

(+++++)

3

Male

1

Same as above

(+++++)

4

Male

2

Same as above

(+++++)

5

Male

1

BV

PBV

TC

 
   

Fer++

(−)

Fer

(+++++)

6

Male

1/12

Fer++

(−)

Fer,Feb

(++++)

7

Female

4

Fer+

(−)

Feb

(+++++)

8

Female

1

No Fc

(−)

Feb

(+++++)

9

Male

11

(−)

Fer+

No Fc

(+++)

10

Male

2

No Fc

(−)

Feb

(+)

11

Female

5

No Fc

(−)

Feb

(++)

12–14

1 Male 2 female

1, 2, 4

No Fc

(−)

15

Female

4

(2) Checked in bone marrow

Clusters of Fc , predominantly Feb, throughout the whole section.

(+++++)

16

Female

3

Same as above

(+++++)

17

Female

4

Same as above

(+++++)

18

Male

3

No Fc

(−)

  1. Abbreviations: (−), tissue not present in section; BV, blood vessels; Feb, Fblasts; Fc, F-cells; Fer, F-erythrocytes; Fer+, low percent of Fer; Fer++, high percent of Fer; PBV, proliferating blood vessels; TC, tumour tissue.