Table 3 Odd ratios and 95% CIs for prostate cancer risk associated with COX2 rs2745557 and NSAID use
From: COX2 genetic variation, NSAIDs, and advanced prostate cancer risk
rs2745557 GG | rs2745557 GA/AA | ||||||
|---|---|---|---|---|---|---|---|
NSAID | Cases, n (%) | Controls, n (%) | OR (95% CI) | Cases, n (%) | Controls, n (%) | OR (95% CI) | |
All groupsa | No | 264 (64.7) | 144 (43.6) | 1.00 | 64 (45.1) | 80 (42.6) | 1.00 |
Yes | 413 (61.0) | 186 (56.4) | 0.58 (0.42–0.79)b | 78 (54.9) | 108 (57.5) | 0.86 (0.55–1.35) | |
African Americansc | No | 44 (63.6) | 24 (42.9) | 1.00 | 14 (70.0) | 22 (66.7) | 1.00 |
Yes | 25 (36.2) | 32 (57.1) | 0.44 (0.21–0.91)d | 6 (30.0) | 11 (33.3) | 0.73 (0.21–2.56) | |
Caucasiansc | No | 119 (40.5) | 77 (29.8) | 1.00 | 50 (41.0) | 58 (37.4) | 1.00 |
Yes | 175 (59.5) | 181 (70.2) | 0.62 (0.43–0.89)e | 72 (59.0) | 97 (62.6) | 0.86 (0.53–1.40) | |
