Table 1 Correlation between MK expression and clinicopathologic factors in pancreatic head carcinoma
From: Clinical significance of midkine expression in pancreatic head carcinoma
| Â | Â | MK expression | Â | |
|---|---|---|---|---|
| Â | Total n =75 | Positive n =40 (53.3%) | Negative n =35 (46.7%) | P -values |
Age (years) | ||||
 Mean±s.d. |  | 67.4±8.9 | 64.9±9.9 | 0.2648 |
Gender | ||||
 Male | 50 (66.7) | 23 (57.5) | 27 (77.1) | 0.0718 |
 Female | 25 (33.3) | 17 (42.5) | 8 (22.9) |  |
Histology | ||||
 Well | 29 (38.7) | 14 (35.0) | 15 (42.9) | 0.2318 |
 Moderately | 43 (57.3) | 23 (57.5) | 20 (57.1) |  |
 Poor | 3 (4.0) | 3 (7.5) | 0 (0.0) |  |
pT | ||||
 pT1 | 3 (4.0) | 1 (2.5) | 2 (5.7) | 0.3699 |
 pT2 | 5 (6.7) | 1 (2.5) | 4 (11.4) |  |
 pT3 | 59 (78.7) | 33 (82.5) | 26 (74.3) |  |
 pT4 | 8 (10.7) | 5 (12.5) | 3 (8.6) |  |
pN | Â | Â | Â | Â |
 Negative | 28 (37.3) | 14 (35.0) | 14 (40.0) | 0.6552 |
 Positive | 47 (62.7) | 26 (65.0) | 21 (60.0) |  |
Liver metastasis | ||||
 Negative | 47 (62.7) | 20 (50.0) | 27 (77.1) | 0.0153 |
 Positive | 28 (37.3) | 20 (50.0) | 8 (22.9) |  |
pStage | ||||
 I | 6 (8.0) | 1 (2.5) | 5 (14.3) | 0.3651 |
 IIA | 21 (28.0) | 13 (32.5) | 8 (22.9) |  |
 IIB | 38 (50.7) | 20 (50.0) | 18 (51.4) |  |
 III | 6 (8.0) | 4 (10.0) | 2 (5.7) |  |
 IV | 4 (5.3) | 2 (5.0) | 2 (5.7) |  |
Lymphatic invasion | ||||
 Negative | 9 (12.0) | 4 (10.0) | 5 (14.3) | 0.5688 |
 Positive | 66 (88.0) | 36 (90.0) | 30 (85.7) |  |
Venous invasion | ||||
 Negative | 19 (25.3) | 5 (12.5) | 14 (40.0) | 0.0063 |
 Positive | 56 (74.7) | 35 (87.5) | 21 (60.0) |  |
Microvessel density | ||||
 Low grade | 33 (44.0) | 11 (27.5) | 22 (62.9) | 0.0021 |
 High grade | 42 (56.0) | 29 (72.5) | 13 (37.1) |  |
