Figure 4 | British Journal of Cancer

Figure 4

From: PLD1 is overexpressed in an ER-negative MCF-7 cell line variant and a subset of phospho-Akt-negative breast carcinomas

Figure 4

Protein-expression profile of tumour specimen no. 22. The matching formalin-fixed, paraffin-embedded (FFPE) tissue for tumour specimen no. 22 (see Figure 2) was sectioned, and protein expression was determined by immunohistochemistry (IHC). The staining profile for this tumour demonstrates that the phospholipase D1 (PLD1)/mammalian target of rapamycin (mTOR)/p70S6K pathway is active in cytokeratin (CK17)-positive tumour cells that are negative for phospho-Akt and ER expression.

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