Table 2 EGFR expression and response to chemotherapy

From: Carcinoma of an unknown primary: are EGF receptor, Her-2/neu, and c-Kit tyrosine kinases potential targets for therapy?

Response

EGFR negative ( n =18)

EGFR positive ( n =36)

P -value

Complete response

0

1 (3%)

 

Partial response

4 (22%)

17 (47%)

 

Stable disease

5 (28%)

9 (25%)

 

Progressive disease

7 (39%)

5 (14%)

 

Not evaluable

2 (1%)

4 (11%)

 

Objective response rate

4 (22%)

18 (50%)

<0.05

  1. EGFR-negative tumour patient: EGFR score 1+.
  2. EGFR-positive tumour patient: EGFR score 2+ or 3+.
Back to article page