Table 3 Sensitivities and specificities of CT, US abdomen, EUS, US neck, and chest X-ray only and the number of false-positive and false-negative results and the accuracy rates plus 95% confidence intervals for CT, US abdomen, EUS, US neck, and chest X-ray only and the combinations of CT and the other investigations in patients with oesophageal or gastric cardia cancer
Sensitivity | Specificity | False-positive: false-negative | Accuracy rate | 95% confidence interval | |
|---|---|---|---|---|---|
Liver (n=335, 26 metastases) | |||||
CT | 19/26 (73%) | 299/309 (97%) | 10 : 7 | 0.95 | 0.92–0.97 |
USa | 17/26 (65%) | 308/309 (99%) | 1 : 9 | 0.97 | 0.95–0.99 |
CT+USa: 1 positive | 10 : 6 | 0.95 | 0.92–0.97 | ||
CT+USa: 2 positive | 1 : 10 | 0.97 | 0.94–0.98 | ||
Celiac lymph nodes (n=143, 32 metastases) | |||||
CT | 22/32 (69%) | 102/111 (92%) | 9 : 10 | 0.87 | 0.80–0.92 |
USa | 14/32 (44%) | 111/111 (100%) | 0 : 18 | 0.87 | 0.81–0.92 |
EUS | 12/32 (38%) | 104/111 (94%) | 7 : 20 | 0.81 | 0.74–0.87 |
CT+EUS: 1 positive | 11 : 6 | 0.88 | 0.82–0.93 | ||
CT+EUS: 2 positive | 5 : 24 | 0.80 | 0.72–0.86 | ||
CT+USa: 1 positive | 9 : 6 | 0.90 | 0.83–0.94 | ||
CT+USa: 2 positive | 0 : 22 | 0.85 | 0.78–0.90 | ||
CT+USa+EUS: ⩾1 positive | 11 : 5 | 0.89 | 0.82–0.93 | ||
CT+USa+EUS: ⩾2 positive | 5 : 13 | 0.87 | 0.81–0.92 | ||
CT+USa+EUS: 3 positive | 0 : 30 | 0.79 | 0.71–0.85 | ||
Supraclavicular lymph nodes (n=546, 58 metastases) | |||||
CT | 16/58 (28%) | 484/488 (99%) | 4 : 42 | 0.92 | 0.89–0.94 |
USn | 49/58 (85%) | 484/488 (99%) | 4 : 9 | 0.98 | 0.96–0.99 |
CT+USn: 1 positive | 7 : 8 | 0.97 | 0.96–0.98 | ||
CT+USn: 2 positive | 1 : 43 | 0.92 | 0.89–0.94 | ||
Lung (n=424, 19 metastases) | |||||
CT | 17/19 (90%) | 399/405 (99%) | 6 : 2 | 0.98 | 0.96–0.99 |
CXR | 13/19 (68%) | 404/405 (99%) | 1 : 6 | 0.98 | 0.97–0.99 |
CT+ CXR: 1 positive | 7 : 0 | 0.98 | 0.97–0.99 | ||
CT+ CXR: 2 positive | 0 : 8 | 0.98 | 0.96–0.99 | ||