Table 1 Characteristics of the study groups

From: Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia

 

No.

VEGF (pg ml−1)

VEGF/PlGF (pg ml−1)

VEGF-C (pg ml−1)

VEGF-D (pg ml−1)

Ang-1 (pg ml−1)

Ang-2 (pg ml−1)

Tie-2 (ng ml−1)

Age

 <45

25

47.85±43.85

8.52±10.63

378.89±258.09

614.55±381.32

1344.02±939.19

3977.02±2741.20

23.89±8.15

 ⩾45

27

31.49±19.37

19.02±37.01

389.53±247.86

879.69±582.55

1509.71±939.30

2936.34±2742.42

21.81±7.60

 P-value

 

0.096

0.168

0.880

0.057

0.528

0.178

0.346

Sex

 Male

33

41.40±36.56

15.45±31.14

391.74±251.72

844.10±560.19

1279.31±800.31

3192.22±2513.06

24.52±8.36

 Female

19

35.81±30.03

11.41±21.78

371.70±254.39

592.64±366.79

1691.86±1103.48

3861.23±3183.72

19.83±6.03

 P-value

 

0.554

0.587

0.785

0.057

0.164

0.438

0.024a

FAB subtype

 M0

2

44.13±35.22

9.09±9.20

282.84±21.65

829.40±517.51

1725.07±915.97

1213.66±585.51

24.32±0.74

 M1

15

35.48±44.46

3.39±3.68

348.72±186.96

764.07±703.42

1480.47±659.10

3283.47±2327.49

23.40±5.71

 M2

17

37.55±25.65

26.76±40.63

417.03±338.62

726.52±462.79

1735.12±1350.26

3362.76±3219.54

20.18±8.67

 M3

7

71.88±37.89

7.80±10.92

413.84±131.58

687.09±279.06

783.75±269.15

3951.64±3160.14

24.29±3.90

 M4

8

26.14±14.28

17.32±31.84

459.35±263.12

667.53±321.93

1464.84±440.60

4131.93±3134.01

24.75±8.85

 M5

2

20.11±1.35

4.35±5.22

89.07±10.65

820.14±272.82

545.18±137.94

3460.07±1308.26

28.80±24.15

 P-value

 

0.133

0.275

0.505

0.996

0.211

0.855

0.583

Cytogenetic subtype

 Favourable

7

55.14±45.01

8.44±10.51

369.97±159.36

702.40±271.53

988.34±848.59

2952.35±2516.61

21.87±5.73

 Intermediate

29

37.08±37.03

18.48±35.32

426.92±301.19

726.98±445.84

1735.36±1029.81

3588.60±3129.72

24.55±9.18

 Unfavourable

16

36.58±21.30

8.22±13.77

313.69±157.26

819.76±688.43

1069.93±535.84

3373.17±2240.56

20.07±5.06

 P-value

 

0.429

0.434

0.351

0.817

0.026a

0.861

0.179

  1. aDenotes significant difference.
  2. Abbreviations: Ang=angiopoietin; ANOVA=analysis of variance; FAB=French–American–British; PlGF=placental growth factor; VEGF=vascular endothelial growth factor.
  3. Age and sex were analysed using Student's t test, and FAB subtypes and cytogenetic subtype were analysed using ANOVA.
  4. Favourable cytogenetic subtype: t(15; 17), t(8; 21), and inv(16); unfavourable: −5, −7, +8, and complex; and intermediate: normal cytogenetic subtype and others.
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