Table 3 Odds ratiosa and 95% confidence intervals for biliary tract cancer in relation to age at gallstone diagnosis and duration of stones, Shanghai, China
From: Gallstones and the risk of biliary tract cancer: a population-based study in China
Controls b | Controls c | Gallbladder cancer | Bile duct cancer | Ampulla of Vater cancer | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
n | n | n | OR | 95% CI | n | OR | 95% CI | n | OR | 95% CI | |
Total | 959 | 902 | 368 | 191 | 68 | ||||||
Duration of gallstones (years) | |||||||||||
No gallstones | 735 | 735 | 60 | 1.0 | — | 64 | 1.0 | — | 32 | 1.0 | — |
⩽1 | 74 | 70 | 138 | 24.5 | 16.4–36.5 | 63 | 10.2 | 6.6–15.7 | 20 | 6.5 | 3.5–12.1 |
2–4 | 23 | 17 | 30 | 23.6 | 12.1–45.8 | 7 | 3.7 | 1.5–9.1 | 2 | 1.7 | 0.4–7.7 |
5–9 | 47 | 30 | 35 | 14.9 | 8.5–26.2 | 11 | 2.9 | 1.4–5.9 | 5 | 2.4 | 1.9–6.5 |
⩾10 | 80 | 50 | 90 | 23.3 | 15.0–36.3 | 37 | 5.6 | 3.5–9.0 | 4 | 1.1 | 1.4–3.2 |
Age at diagnosis of gallstones | |||||||||||
No gallstones | 735 | 735 | 60 | 1.0 | — | 63 | 1.0 | — | 32 | 1.0 | — |
<45 | 28 | 18 | 41 | 25.5 | 13.6–47.8 | 16 | 6.2 | 3.2–12.2 | 1 | 0.8 | 0.1–6.4 |
45–59 | 82 | 53 | 82 | 19.2 | 12.4–29.7 | 42 | 6.0 | 3.8–9.4 | 9 | 2.6 | 1.2–5.6 |
⩾60 | 114 | 96 | 173 | 24.0 | 16.2–35.6 | 62 | 7.2 | 4.7–11.1 | 21 | 4.2 | 2.3–7.8 |
Age at diagnosis of gallstones and duration of gallstones | |||||||||||
No gallstones | 735 | 735 | 60 | 1.0 | — | 64 | 1.0 | — | 32 | 1.0 | |
<55, ⩽1 year | 8 | 7 | 12 | 16.1 | 5.7–45.3 | 7 | 8.8 | 2.8–27.1 | 2 | 8.3 | 1.4–49.1 |
<55, 2–5 years | 2 | 2 | 5 | 22.1 | 4.1–120.3 | 2 | 9.3 | 1.3–68.7 | 1 | 16.5 | 1.3–204.3 |
<55, ⩾6 years | 60 | 38 | 79 | 25.6 | 16.0–38.8 | 33 | 6.5 | 3.9–10.6 | 4 | 1.7 | 0.6–5.1 |
⩾55, ⩽1 year | 66 | 63 | 126 | 25.4 | 16.7–38.8 | 56 | 10.3 | 6.6–16.2 | 18 | 6.8 | 3.5–12.9 |
⩾55, 2–5 years | 34 | 26 | 34 | 17.7 | 9.7–32.2 | 8 | 2.9 | 1.3–6.7 | 2 | 1.5 | 0.3–6.8 |
⩾55, ⩾ 6 years | 54 | 31 | 37 | 16.8 | 9.4–30.0 | 12 | 2.8 | 1.4–5.6 | 4 | 1.7 | 0.6–5.2 |
