Table 4 Odds ratiosa and 95% confidence intervals for biliary tract cancer in relation to gallstones and other factors, Shanghai, China
From: Gallstones and the risk of biliary tract cancer: a population-based study in China
Biliary tract cancer | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Controls | Gallbladder | Extrahepatic bile duct | Ampulla of Vater | ||||||||
n b | n c | n | OR | 95% CI | n | OR | 95% CI | n | OR | 95% CI | |
Gallstones and chronic cholecystitis d | |||||||||||
No gallstones, no cholecystitis | 693 | 693 | 47 | 1.0 | — | 59 | 1.0 | — | 27 | 1.0 | — |
Chronic cholecystitis only | 32 | 32 | 4 | 2.0 | 0.7–5.8 | 2 | 0.9 | 0.2–3.9 | 2 | 1.8 | 0.4–8.1 |
Gallstones only | 182 | 136 | 185 | 20.9 | 14.2–30.7 | 84 | 6.5 | 4.4–9.7 | 31 | 5.0 | 2.8–8.7 |
Gallstones and chronic cholecystitis | 38 | 29 | 65 | 34.3 | 19.9–59.2 | 24 | 9.6 | 5.2–17.6 | 3 | 2.8 | 0.8–9.8 |
P-interaction | 0.78 e | 0.54 | 0.23 | ||||||||
Gallstones and pancreatitis | |||||||||||
No gallstones, no pancreatitis | 730 | 730 | 59 | 1.0 | — | 62 | 1.0 | 29 | 1.0 | — | |
Pancreatitis only | 4 | 4 | 1 | 3.0 | 0.3–28.0 | 1 | 2.4 | 0.2–23.3 | 0 | — | |
Gallstones only | 214 | 163 | 292 | 23.2 | 16.5–32.6 | 116 | 7.8 | 5.4–11.3 | 33 | 4.4 | 2.6–7.5 |
Gallstones and pancreatitis | 10 | 4 | 6 | 20.8 | 5.6–77.6 | 7 | 8.7 | 3.2–24.2 | 1 | 2.5 | 0.3–20.5 |
P-interaction | 0.37 | 0.55 | 0.99 | ||||||||
Gallstones and BMI | |||||||||||
No gallstones, BMI <23 | 399 | 399 | 31 | 1.0 | — | 36 | 1.0 | 15 | 1.0 | ||
No gallstones, BMI ⩾23 | 335 | 335 | 28 | 1.1 | 0.6–1.8 | 27 | 0.9 | 0.6–1.6 | 17 | 1.4 | 0.7–2.8 |
Gallstones, BMI <23 | 77 | 62 | 115 | 25.2 | 15.4–41.2 | 57 | 9.8 | 5.9–16.4 | 15 | 5.7 | 2.6–12.3 |
Gallstones, BMI ⩾ 23 | 147 | 105 | 191 | 25.0 | 15.8–39.3 | 69 | 6.6 | 4.1–10.6 | 21 | 4.5 | 2.2–9.1 |
P-interaction | 0.79 | 0.36 | 0.28 | ||||||||
Gallstones and diabetes | |||||||||||
No gallstones, no diabetes | 688 | 688 | 55 | 1.0 | — | 61 | 1.0 | — | 31 | 1.0 | — |
Diabetes only | 47 | 47 | 5 | 1.5 | 0.6–4.0 | 3 | 0.8 | 0.3–2.8 | 1 | 0.5 | 0.1–3.8 |
Gallstones only | 193 | 146 | 262 | 23.8 | 16.7–34.0 | 110 | 7.9 | 5.4–11.5 | 32 | 4.2 | 2.4–7.1 |
Gallstones and diabetes | 31 | 21 | 46 | 30.7 | 16.7–56.5 | 17 | 8.0 | 4.0–15.9 | 4 | 3.3 | 1.1–10.1 |
P-interaction | 0.79 | 0.78 | 0.71 | ||||||||
