Table 1 Distribution of baseline factors of all patients and correlation between TMPRSS2:ERG gene fusion, histologic grade, pathologic stage and PSA level at diagnosis
TMPRSS2:ERG gene fusion expression | ||||
---|---|---|---|---|
Prognostic factor | All patients ( n =165) | Positive ( n =81) | Negative ( n =84) | P -value |
Histologic grade | ||||
Gleason Score 5–6 | 41 | 21 (51.2%) | 20 (48.7%) | 0.67 |
Gleason Score 7 | 113 | 56 (49.6%) | 57 (50.4%) | |
Gleason Score 8–10 | 11 | 4 (36.3%) | 7 (63.6%) | |
Pathologic stage | ||||
Organ confined | 74 | 35 (47.3%) | 39 (52.7%) | 0.92 |
Extracapsular extension | 79 | 40 (50.6%) | 39 (49.4%) | |
Seminal vesicle involvement | 12 | 6 (50%) | 6 (50%) | |
PSA level at diagnosis (ng ml−1) | ||||
Mean (s.d.) | 9.3 (7.3) | 9.5 (5.7) | 9.1 (8.6) | 0.73 |
Median | 7.3 | 8.0 | 7.0 | 0.14 |
Range | 2.1–64 | 3.0–38.9 | 2.1–64 |