Table 1 Presentation of lung metastasis on day 14 after tumour cell injection

From: COX-2 inhibitor celecoxib prevents chronic morphine-induced promotion of angiogenesis, tumour growth, metastasis and mortality, without compromising analgesia

 

Dead mice

Live mice

Total (dead+live)

PBS

6/6

8/14

14/20

70%

Morphine

12/12

6/6

18/18

100%

Celecoxib

0/2

3/10

3/12

25%

Celecoxib+morphine

2/2

4/16

6/18

33%

  1. Metastasis was examined in the H&E stained lung sections of mice that died on day 14 and in the lungs of mice remaining alive. Data are expressed as number of mice with lung metastasis/number of mice in the specific treatment group on day 14 (alive and/or dead).
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