Table 1 Patient demographics
Variable | No. of patients (%) |
|---|---|
Enrolled | 46 |
Dose Level 1 | 37 (80) |
Dose Level 2 | 9 (20) |
Age (years) | |
Median | 63 |
Range | 43–78 |
Gender | |
Male | 29 (63) |
Female | 17 (37) |
Performance status (ECOG) | |
Median | 1 |
0 | 8 (18) |
1 | 25 (54) |
2 | 13 (28) |
Primary tumour site | |
Pancreatic cancer | 13 (28) |
Biliary tract cancer | 10 (22) |
Colorectal cancer | 7 (15) |
Oesophageal cancer | 7 (15) |
Cancer of unknown primary | 3 (7) |
Head and neck tumour | 3 (7) |
Gastric cancer | 1 (2) |
Hepatocellular carcinoma | 1 (2) |
Small intestinal cancer | 1 (2) |
Prior chemotherapy | |
1 Line | 25 (54) |
2 Lines | 7 (15) |
⩾3 Lines | 14 (31) |
5-FU based (i.v. or oral) | 25 (54) |
Tumour localisation | |
Primary | 19 (41) |
Liver | 34 (74) |
Lung | 14 (30) |
Lymph nodes | 19 (41) |
Bone | 8 (17) |
Peritoneal carcinomatosis | 5 (11) |
