Figure 4

Peptide-specific cytotoxicity against cancer cells. Purified CD8+ T cells from peptide-stimulated PBMCs of HLA-A3 supertype+ patients were tested for their cytotoxicity against HLA-A11+ SQ-1 cells or HLA-A31+/A33+ LC-1 cells in the presence of unlabelled C1R-A11, -A31, or -A33 cells, which were pre-loaded with either the corresponding peptide or the HIV peptide, by a 6-h 51Cr-release assay. *Statistically significant at P<0.05.