Table 4 Number of deaths (N) and mortality rates (R) per million person–years at risk by time period and diagnostic group at ages 13–29 years in England and Wales, 1981–2005
From: Cancer mortality in 13 to 29-year-olds in England and Wales, 1981–2005
1981–1985 | 1986–1990 | 1991–1995 | 1996–2000 | 2001–2005 | P-value | APC a | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Main group | Subgroup | N | R | N | R | N | R | N | R | N | R | Heter. | Trend | value | (95% CI) |
Lip, oral cavity and pharynx | 63 | 1.0 | 69 | 1.0 | 53 | 0.9 | 57 | 1.0 | 50 | 0.9 | 0.7776 | 0.5251 | −0.54 | (−1.64,0.56) | |
Digestive organs | 298 | 4.8 | 317 | 4.8 | 253 | 3.9 | 247 | 4.2 | 221 | 3.9 | 0.0226 | 0.0053 | −0.92* | (−1.82,0.00) | |
Colorectal | 116 | 1.9 | 120 | 1.8 | 82 | 1.2 | 104 | 1.8 | 84 | 1.5 | 0.0330 | 0.1086 | −0.41 | (−1.87,1.06) | |
Liver | 66 | 1.0 | 71 | 1.1 | 58 | 0.9 | 52 | 0.9 | 65 | 1.1 | 0.6814 | 0.9109 | −0.13 | (−1.86,1.63) | |
Other sites in GI tract | 116 | 1.9 | 126 | 1.9 | 113 | 1.7 | 91 | 1.5 | 72 | 1.3 | 0.0466 | 0.0028 | −1.66* | (−3.05,−0.25) | |
Respiratory and intrathoracic organs | 139 | 2.3 | 90 | 1.4 | 74 | 1.1 | 63 | 1.1 | 53 | 0.9 | <0.0001 | <0.0001 | −4.26* | (−5.56,−2.94) | |
Bone and articular cartilage | 414 | 6.2 | 331 | 5.2 | 280 | 4.8 | 280 | 5.1 | 320 | 5.6 | 0.0104 | 0.1444 | −0.49 | (−1.31,0.34) | |
Melanoma of skin | 167 | 2.7 | 165 | 2.4 | 183 | 2.8 | 134 | 2.3 | 135 | 2.4 | 0.3428 | 0.2319 | −0.64 | (−1.69,0.43) | |
Mesothelial and soft tissue | 231 | 3.6 | 258 | 3.9 | 232 | 3.8 | 190 | 3.4 | 171 | 3.0 | 0.0648 | 0.0339 | −0.86 | (−1.76,0.05) | |
Breast | 176 | 3.0 | 174 | 2.6 | 151 | 2.2 | 127 | 2.0 | 92 | 1.6 | <0.0001 | <0.0001 | −2.62* | (−3.48,−1.75) | |
Genitourinary organs | 623 | 10.1 | 560 | 8.4 | 412 | 6.2 | 311 | 5.2 | 253 | 4.5 | <0.0001 | <0.0001 | −4.24* | (−4.90,−3.56) | |
Cervix | 207 | 7.0 | 199 | 5.9 | 159 | 4.6 | 115 | 3.7 | 93 | 3.3 | <0.0001 | <0.0001 | −4.07* | (−5.20,−2.92) | |
Ovary | 116 | 3.7 | 87 | 2.6 | 85 | 2.6 | 70 | 2.4 | 52 | 1.8 | 0.0003 | <0.0001 | −2.80* | (−4.02,−1.57) | |
Testis | 207 | 6.6 | 183 | 5.4 | 106 | 3.3 | 75 | 2.6 | 50 | 1.8 | <0.0001 | <0.0001 | −6.31* | (−7.48,−5.11) | |
Other sites | 93 | 1.5 | 91 | 1.4 | 62 | 1.0 | 51 | 0.9 | 58 | 1.0 | 0.0039 | 0.0009 | −2.60* | (−4.10,−1.07) | |
Eye, brain, and other parts of CNS | 559 | 8.8 | 609 | 9.4 | 534 | 8.7 | 435 | 7.6 | 462 | 8.1 | 0.0170 | 0.0141 | −0.74* | (−1.47,−0.01) | |
Thyroid and other endocrine glands | 62 | 1.0 | 64 | 1.0 | 70 | 1.2 | 50 | 0.9 | 43 | 0.8 | 0.2553 | 0.2294 | −0.77 | (−3.11,1.62) | |
Lymphoid, haematopoietic and related tissue | 1858 | 28.8 | 1636 | 25.1 | 1461 | 23.8 | 1106 | 19.7 | 959 | 16.9 | <0.0001 | <0.0001 | −2.57* | (−2.93,−2.22) | |
Lymphoid leukaemia | 469 | 7.1 | 463 | 7.3 | 385 | 6.6 | 346 | 6.3 | 265 | 4.6 | <0.0001 | <0.0001 | −1.81* | (−2.62,−0.99) | |
Myeloid and monocytic leukaemia | 555 | 8.6 | 463 | 7.1 | 387 | 6.3 | 312 | 5.5 | 281 | 4.9 | <0.0001 | <0.0001 | −2.70* | (−3.42,−1.97) | |
Hodgkin's lymphoma | 397 | 6.3 | 335 | 5.0 | 270 | 4.2 | 139 | 2.4 | 137 | 2.4 | <0.0001 | <0.0001 | −5.12* | (−6.07,−4.15) | |
Non-Hodgkin's lymphoma | 362 | 5.6 | 331 | 5.0 | 382 | 6.0 | 271 | 4.8 | 239 | 4.2 | <0.0001 | 0.0008 | −1.20* | (−2.11,−0.28) | |
Other and unspecified | 75 | 1.2 | 44 | 0.7 | 37 | 0.6 | 38 | 0.7 | 37 | 0.6 | 0.0029 | 0.0034 | −3.31* | (−5.26,−1.32) | |
Other malignant neoplasms | 166 | 2.6 | 141 | 2.1 | 195 | 3.0 | 166 | 2.8 | 158 | 2.8 | 0.0189 | 0.1097 | 0.46 | (−0.81,1.75) | |
Benign and uncertain behaviour | 235 | 3.7 | 145 | 2.2 | 172 | 2.9 | 181 | 3.2 | 142 | 2.5 | <0.0001 | 0.0435 | −1.02 | (−2.35,0.32) | |
Eye, brain, and other parts of CNS | 112 | 1.8 | 61 | 0.9 | 75 | 1.2 | 73 | 1.3 | 67 | 1.2 | 0.0012 | 0.0690 | −1.61 | (−3.50,0.32) | |
Other sites | 123 | 1.9 | 84 | 1.3 | 97 | 1.6 | 108 | 1.9 | 75 | 1.3 | 0.0075 | 0.2782 | −0.38 | (−1.82,1.09) | |
All groups | 4991 | 78.4 | 4559 | 69.5 | 4070 | 65.2 | 3347 | 58.5 | 3059 | 53.9 | <0.0001 | <0.0001 | −1.86* | (−2.09,−1.62) | |
