Table 2 Response according to various clinical and pathological parameters

From: Biological predictive factors in rectal cancer treated with preoperative radiotherapy or radiochemotherapy

Parameter

Response

%

No response

%

P -value

Tumour stage

    

0.71

 T1–2

2

17

10

83

 

 T3–4

11

26

31

74

 

Nodal status

    

0.004

 N0

9

47

10

53

 

 N1–2

3

9

30

91

 

Treatment

    

0.002

 RT

4

10

34

90

 

 RCT

9

47

10

53

 

TS

    

0.20

 Low

3

14

18

86

 

 High

10

32

21

68

 

P53

    

0.71

 Negative

2

15

11

85

 

 Positive

11

26

31

74

 

VEGF

    

0.31

 Negative

7

33

14

67

 

 Positive

5

17

24

83

 

P21

    

0.74

 Negative

4

18

18

82

 

 Positive

8

25

24

75

 

MLH1

    

0.15

 Preserved

12

29

29

71

 

 Altered

1

7

13

93

 

MSH2

    

0.71

 Preserved

11

26

31

74

 

 Altered

2

15

11

85

 
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