Figure 1

Pattern of positive staining of TPO, HBME, and DPP4. (A) Staining of TPO in benign follicular adenoma: brown granular deposit all over the cytoplasm and around the nuclei. (B) Staining of HBME in papillary cancer: brown reaction predominant on cellular membranes. (C) Staining of DPP4 in papillary cancer: contrasted red reaction within cytoplasm and along membranes.