Table 3 Cox regression analysis with inclusion of HDAC2 expression (n=145)

From: Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy

 

Overall survival

 

HR

95%CI

P -value

HDAC2 expression

   

 Low

1.000

  

 High

2.363

1.150–4.856

0.019

Pre-OP PSA

   

 ⩽10 ng ml−1

1.000

  

 >10 ng ml−1

1.542

0.884–2.691

0.127

Tumour stage

   

 pT2

1.000

  

 pT3/pT4

1.557

0.830–2.919

0.168

Gleason sum

   

 2–6

1.000

  

 7

2.795

1.325–5.898

0.007

 8–10

3.131

1.403–6.989

0.005

R-status

   

 R0

1.000

  

 R1

1.440

0.789–2.631

0.235

  1. CI=confidence interval; HDAC=histone deacetylase; HR=hazard ratio.
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