Table 4 Multivariate Cox regression hazards model for time to recurrence
(A) Prognostic indices/model including vascular invasion {enter function} ( n) | HR | 95% CI | P -value |
|---|---|---|---|
Grades 1 and 2 (112) | 1 | ||
Grades 3 and 4 (48) | 2.94 | 1.62–5.36 | <0.01* |
No capsular invasion present (134) | 1 | ||
Capsular invasion present (26) | 4.22 | 2.26–7.90 | <0.01* |
No vascular invasion present (97) | 1 | ||
Vascular invasion present (63) | 1.74 | 0.88–3.46 | 0.113 |
Caveolin/AKT covariate negative (137) | 1 | ||
Caveolin/AKT covariate positive (23) | 2.13 | 1.15–3.92 | <0.02* |
(B) Prognostic indices/model excluding vascular invasion {forward conditional} ( n) | HR | 95% CI | P -value |
Grades 1 and 2 (112) | 1 | ||
Grades 3 and 4 (48) | 3.58 | 2.05–6.24 | <0.001* |
No capsular invasion present (134) | 1 | ||
Capsular invasion present (26) | 5.17 | 2.88–9.29 | <0.001* |
Caveolin/AKT covariate negative (137) | 1 | ||
Caveolin/AKT covariate positive (23) | 2.26 | 1.23–4.16 | 0.009* |
