Table 1 Comparison of cortactin and EGFR status to demographic, clinical, and pathologic data

From: Prognostic significance of cortactin levels in head and neck squamous cell carcinoma: comparison with epidermal growth factor receptor status

 

Cortactin status a

EGFR status a

 

n

+

P

n

+

P

Patient cohort

        

Age (years) 37–82 (median 63)

 Interpretable for cortactin

176

99

77

     

 Interpretable for EGFR

    

176

66

110

 

Positive control

 Interpretable for cortactin

7

0

7

     

 Noninterpretable

1

       

 Interpretable for EGFR

    

9

2

7

 

 Noninterpretable

    

2

   

Gender

 Male

138

76

62

0.11

138

36

102

0.13

 Female

38

23

15

 

38

30

8

 

Site

 Oral cavity

40

20

20

0.42

40

10

30

0.39

 Pharynx

57

42

15

 

57

21

36

0.11

 Larynx

79

66

13

 

79

35

39

 

TNM stage

 I

34

15

19

0.005

34

24

10

0.004

 II

44

19

25

 

44

20

24

 

 III

48

15

23

 

48

16

32

 

 IV

50

12

38

 

50

14

36

 

Grade

 Well differentiated

27

15

12

0.001

27

16

11

0.001

 Moderately differentiated

94

24

70

 

94

34

60

 

 Poorly differentiated

55

11

44

 

55

11

44

 
  1. EGFR=epidermal growth factor receptor; TNM=tumour node metastasis.
  2. aCortactin/EGFR status: (−)=nonoverexpressor; (+)=overexpressor.
  3. †Significant at the 0.01 level.