Table 6 Subsequent treatments after failure to respond to gefitinib (n=28)

From: Multicentre prospective phase II trial of gefitinib for advanced non-small cell lung cancer with epidermal growth factor receptor mutations: results of the West Japan Thoracic Oncology Group trial (WJTOG0403)

Gefitinib treatment

No. of Patients

1st regimen after gefitinib

No. of patients

2nd regimen after gefitinib

No. of patients

1st line

17

Plt doublet

5

Gem or Doce

2

    

Gefitiniba

1

  

VNR

1

—

-

2nd lineb

4

Doce

2

Doce

1

  

Plt doublet

1

Doce

1

2nd line

5

Doce

1

Gefitiniba

1

3rd line

2

—

—

—

—

Total

28

 

10

  

Response

  

4/10

 

2/6

  1. Doce=docetaxel; Gem=gemcitabine; Plt=platinum; VNR=vinorelbine.
  2. aBoth patients had an SD response after gefitinib re-treatment.
  3. bFirst regimen as systemic chemotherapy after adjuvant treatment.
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