Figure 2

Elevated relative expression of hY RNAs in human cancer tissue compared to corresponding normal nonmalignant tissues. Expression levels of the indicated RNAs were determined by qRT–PCR relative to HPRT mRNA in extracts from 24 individual normal tissue samples and 42 individual carcinomas and adenocarcinomas. (A) Distributions of relative RNA expression levels. Box and whisker plots are shown for the distributions of relative expression levels for each RNA as indicated. Thin vertical lines indicate range, boxes indicate the 25th–75th percentile and black horizontal lines indicate the median for each distribution. Light grey boxes represent normal sample distributions, dark grey boxes represent tumour sample distributions. (B) Elevated hY RNA expression in tumours. The relative expression of these RNAs in tumour samples compared to corresponding normal tissue samples was calculated by dividing the mean expression level of all tumour samples by the mean value of the normal nonmalignant samples.