Figure 1

Scheme of the therapy. CT, chemotherapy; Ext RT, external beam radiation therapy. Method A: wide field irradiation, 36–40 Gy/20 fraction. Method B: reduced field irradiation, 26–30 Gy/15 fraction. Brachy, brachytherapy. Alternating therapy involving systemic chemotherapy and radiation therapy is performed. Intra-arterial chemotherapy is initiated after the end of the second course of systemic chemotherapy in the Groups 2 and 4.