Figure 3 | British Journal of Cancer

Figure 3

From: Assessment of 1183 screen-detected, category 3B, circumscribed masses by cytology and core biopsy with long-term follow up data

Figure 3

Biopsy features of a fibroadenoma accompanied by a focus of high grade DCIS. (A) Low power view of a smear showing cohesive clusters of orderly cells (arrow), together with a dispersed population of large, atypical cells (left side of picture). (B) Higher power view of a small cluster of atypical cells, showing nuclear enlargement, variability and irregularity of nuclear membranes. (C) Core biopsy showing a fibroadenoma accompanied by one focus of high-grade DCIS (arrow). (D) Higher power view of the area of DCIS arising in a fibroadenoma. High-grade nuclear features and comedo necrosis are evident.

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