Table 1 Markers used in CEC assays
From: Circulating endothelial cells in oncology: pitfalls and promises
Marker | Description | Subtype association | Expression level | Coexpression | References |
---|---|---|---|---|---|
CD31 | PECAM-1 | Pan-endothelial | ++a | P, Pan-leukocyte | |
CD34 | Stem cell marker | Pan-endothelial | ++a | S | |
CD36 | Collagen receptor I | Micro vascular | +a | P, E, M, D | |
CD54 | ICAM-1 | Inflammation | +a | L, M | |
CD62-E | E-selectin | Inflammation | ++ | — | |
CD62-P | P-selectin | Inflammation | + | P | |
CD105 | Endoglin | Angiogenesis, malignant | ++a | S, Mb | |
CD106 | VCAM-1 | Inflammation, malignant | +a | — | |
CD137 | ILA/4 | Malignant | + | Lb, D | |
CD144 | VE-cadherin | Pan-endothelial | +a | — | |
CD146 | MelCAM | Pan-endothelial | ++a | Lb | |
CD202b | Tie-2 | Angiogenesis | (+)a | — | |
CD276 | B7-H3 | Malignant | + | D, Mb | |
CD309 | VEGFR-2 | Angiogenesis | (+)a | S | |
VWF | Â | Pan-endothelial | ++a | P | |
UEA-1 |  | Pan-endothelial | ++ | — | |
DiL-AcLDL |  | Pan-endothelial | ++ | — |