Table 4 Factors associated with risk of death among colorectal cancer patients diagnosed during 1994–2002, stratified by receipt of surgery: HRs,a 95% CIs, and P-values

From: Inequity in colorectal cancer treatment and outcomes: a population-based study

 

No surgeryb (n =3373)

Surgeryb (n =11876)

 

HR (95% CI)

HR (95% CI)

Sex

  

 Male

1.00

1.00

 Female

0.90 (0.84, 0.98)

0.81 (0.77, 0.85)

 

P=0.010

P<0.001

Age

  

 <55

1.00

1.00

 55–64

1.10 (0.94, 1.29)

1.12 (1.02, 1.23)

 65–74

1.41 (1.22, 1.63)

1.42 (1.30, 1.55)

 75+

1.70 (1.47, 1.96)

2.16 (1.97, 2.37)

 

P<0.001

P<0.001

Stage

  

 I

0.48 (0.32, 0.71)

0.36 (0.33, 0.40)

 II

0.76 (0.58, 0.98)

0.58 (0.54, 0.62)

 III

1.00

1.00

 IV

2.31 (1.91, 2.78)

2.83 (2.64, 3.03)

 Unknown

1.33 (1.10, 1.61)

0.69 (0.63, 0.76)

 

P<0.001

P<0.001

Marital status

  

 Married

1.00

1.00

 Not married/unknown

1.12 (1.04, 1.21)

1.12 (1.06, 1.18)

 

P=0.005

P<0.001

Smoking status

  

 Non-smoker/unknown

1.00

1.00

 Current smoker

1.09 (1.00, 1.20)

1.14 (1.07, 1.22)

 Ex-smoker

1.10 (0.99, 1.22)

1.03 (0.96, 1.10)

 

P=0.061

P<0.001

Grade

  

 Well

1.00

1.00

 Moderate

0.94 (0.79, 1.13)

1.06 (0.97, 1.16)

 Poor/undifferentiated

1.43 (1.17, 1.75)

1.40 (1.27, 1.56)

 Missing

1.15 (0.96, 1.36)

1.12 (1.01, 1.25)

 

P<0.001

P<0.001

Period of diagnosis

  

 1994–96

 

1.00

 1997–99

0.87 (0.82, 0.92)

 2000–02

 

0.82 (0.76, 0.87)

  

P<0.001

  1. CI=confidence interval; HR=hazard ratio.
  2. aAll HRs adjusted for factors shown in relevant column (other than site), plus health board and site (colon/rectum).
  3. bModels also stratified by receipt of chemotherapy and radiotherapy.