Table 5 Risk of death by adjuvant treatmenta for colorectal cancers diagnosed during 1994–2002: HRs with 95% CIs

From: Inequity in colorectal cancer treatment and outcomes: a population-based study

 

Stage II

Stage III

Stage IV

Stage unknown

 

HR

95% CI

HR

95% CI

HR

95% CI

HR

95% CI

Chemotherapy: colorectal cancer

 All patientsb

0.88

(0.77, 1.01)

0.67

(0.61, 0.75)

0.83

(0.76, 0.91)

1.23

(1.03, 1.47)

 Surgical patientsc

0.96

(0.84, 1.10)

0.69

(0.62, 0.76)

0.77

(0.68, 0.88)

1.57

(1.23, 2.00)

Radiotherapy: rectal cancer

 All patients: any radiotherapyd,e

1.23

(0.98, 1.55)

1.06

(0.90, 1.24)

0.97

(0.83, 1.14)

1.15

(0.94, 1.40)

 Surgical patients: any radiotherapyc,d

1.09

(0.88, 1.35)

0.88

(0.75, 1.04)

0.79

(0.62, 1.00)

1.41

(1.03, 1.94)

 Surgical+radiotherapy patients: pre-operative radiotherapyf

1.03

(0.63, 1.66)

0.61

(0.42, 0.91)

0.70

(0.40, 1.25)

0.60

(0.36, 1.02)

  1. CI=confidence interval; HR=hazard ratio.
  2. aTreatment received within 1 year of diagnosis.
  3. bHazard ratios adjusted for age, sex, marital status, smoking status, health board, tumour extent (T), nodes (N), site, surgery receipt (yes/no), and radiotherapy (time-dependant covariate).
  4. cHazard ratios adjusted for age, sex, marital status, smoking status, health board, tumour extent (T), nodes (N), and site.
  5. dPre- or post-operative radiotherapy vs no radiotherapy.
  6. eHazard ratios adjusted for age, sex, marital status, smoking status, health board, tumour extent (T), nodes (N), surgery receipt (yes/no), and chemotherapy (time-dependant covariate).
  7. fComparison of pre- vs post-operative radiotherapy among patients treated with surgery and radiotherapy; HR adjusted for age, sex, marital status, smoking status, health board, tumour extent (T), and nodes (N).