Figure 6 | British Journal of Cancer

Figure 6

From: Identification of claudin-4 as a marker highly overexpressed in both primary and metastatic prostate cancer

Figure 6

Immunohistochemical staining of AMACR, claudin-4 and PSMA representative of that observed in a range of prostate conditions. Adjacent sections were stained with haematoxylin and eosin (H and E), AMACR, claudin-4 and PSMA for each prostate tissue examined. Tissue sections consist of a normal (A), BPH (B), HG-PIN without invasive carcinoma (C), HG-PIN with invasive carcinoma (D and E) and metastatic carcinoma (lymph node; F). (A and B) Arrows indicate benign glands; (C) arrow indicates HG-PIN; (D) black arrow indicates HG-PIN and red arrow indicates PCa (Gleason 3+4); (E) black arrow indicates benign epithelial cells and red arrow indicates PCa (Gleason 5+5); (F) arrow indicates cancerous cells present at a metastatic site.

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