Figure 2
From: MT1-MMP regulates urothelial cell invasion via transcriptional regulation of Dickkopf-3

Effect of MMP and protease inhibitors on invasion of various cell lines. (A) A total of 5 × 104 cells incubated in control media or in the presence of various inhibitors (aprotinin, BB94, TIMP1 or TIMP2) for 24 h and the number of cells invading through the Matrigel counted. (B) Effects of TIMP1 and TIMP2 on invasion of EJ28 cells; **P<0.0005 between TIMP2 and control group.