Table 3 Cox proportional hazards regression modelling of the association between in utero IR exposure and childhood cancer in the offspring of female RTs (n=81 262)
From: Childhood cancer in the offspring born in 1921–1984 to US radiologic technologists
Cancer type | Person-years | Cases | HR a | 95% CI | P -trend |
|---|---|---|---|---|---|
Leukaemia | |||||
0 mGy | 637 994 | 28 | 1.0 | ref. | |
>0–0.17 mGy | 369 381 | 17 | 1.1 | 0.6–2.0 | |
0.18–1.0 mGy | 381 244 | 15 | 0.9 | 0.5–1.8 | |
1.01–12.6 mGy | 56 252 | 3 | 1.1 | 0.3–3.7 | 0.72 |
Lymphoma | |||||
0 mGy | 637 994 | 14 | 1.0 | ref. | |
>0–0.17 mGy | 369 381 | 16 | 2.3 | 1.1–4.9 | |
0.18–1.0 mGy | 381 244 | 14 | 1.8 | 0.9–3.9 | |
1.01–12.6 mGy | 56 252 | 4 | 2.7 | 0.9–8.7 | 0.32 |
Solid tumours | |||||
0 mGy | 637 994 | 51 | 1.0 | ref. | |
>0–0.17 mGy | 369 381 | 30 | 1.0 | 0.6–1.6 | |
0.18–1.0 mGy | 381 244 | 29 | 0.9 | 0.6–1.5 | |
1.01–12.6 mGy | 56 252 | 5 | 1.2 | 0.5–3.1 | 0.44 |
Childhood cancers overall | |||||
0 mGy | 637 994 | 93 | 1.0 | ref. | |
>0–0.17 mGy | 369 381 | 63 | 1.2 | 0.9–1.7 | |
0.18–1.0 mGy | 381 244 | 58 | 1.1 | 0.8–1.5 | |
1.01–12.6 mGy | 56 252 | 12 | 1.4 | 0.8–2.6 | 0.41 |
