Table 4 Standardised incidence ratios comparing childhood cancer incidence rates in the offspring of RTs to SEER and Connecticut registry rates (n=100 115)a

From: Childhood cancer in the offspring born in 1921–1984 to US radiologic technologists

 

Offspring of females

Offspring of males

 

Males

Females

Males

Females

 

O

E

O/E (95% CI)

O

E

O/E (95% CI)

O

E

O/E (95% CI)

O

E

O/E (95% CI)

SEER registry comparison

 Leukaemia

37

30

1.2 (0.9–1.7)

26

24

1.1 (0.7–1.6)

11

9

1.3 (0.6–2.2)

8

7

1.2 (0.5–2.4)

 Lymphoma

33

20

1.7b (1.2–2.4)

14

14

1.0 (0.6–1.7)

10

6

1.7 (0.8–3.1)

3

4

0.8 (0.2–2.2)

 All sites

120

114

1.1 (0.9–1.3)

101

99

1.0 (0.8–1.2)

39

33

1.2 (0.8–1.6)

24

29

0.9 (0.5–1.3)

Connecticut registry comparison

 Leukaemia

37

32

1.2 (0.8–1.6)

26

24

1.1 (0.7–1.6)

11

9

1.2 (0.6–2.1)

8

7

1.2 (0.5–2.3)

 Lymphoma

33

21

1.6b (1.1–2.2)

14

14

1.0 (0.5–1.7)

10

6

1.6 (0.8–2.9)

3

4

0.7 (0.2–2.1)

 All sites

120

113

1.1 (0.9–1.3)

101

99

1.0 (0.8–1.2)

41

36

1.1 (0.8–1.5)

24

28

0.9 (0.6–1.3)

  1. E=expected; O=observed; RT=radiologic technologist; SEER=Surveillance Epidemiology and End Results.
  2. aExcludes data on 5826 subjects with missing gender or whose parent reported a race other than white.
  3. bP<0.05.