Figure 1

Schematic view of immunisations and tumour challenge. BALB/c mice were immunised three times intraperitoneally with 0.1 × LD50 of each Listeria-based Mage-b vaccine strain or with the vector control strain LM-LLO, or saline, with 1-week time intervals. Four days after the second immunization, mice were injected with 105 4T1 tumour cells in a mammary fat pad. Two weeks after tumour challenge, mice were euthanized and analysed.