Table 1 Results of the questionnaire survey showing the methodology of estimation of GFR in the UK CCLG centres

From: Estimation of renal function and its potential impact on carboplatin dosing in children with cancer

Centre

Radioisotope

Route of injection

No of samples

Early sampling (<2 h)

GFR estimation

Methodology

Correction factor

 1

51Cr-EDTA

Peripheral

3

Yes

Med Physics

Slope–intercept

BM

 2

51Cr-EDTA

Central

2

No

Biochemistry

Slope–intercept

Chantler

 3

51Cr-EDTA

Central

2

No

Biochemistry

Slope–intercept

Chantler

 4

51Cr-EDTA

Central

4

No

Med Physics

Slope–intercept

Chantler

 5

51Cr-EDTA

Peripheral

4

No

Med Physics

Slope–intercept

BM

 6

51Cr-EDTA

Both

4

Yes

Med Physics

Slope–intercept

BM

 7

51Cr-EDTA

Both

3

No

Med Physics

Slope–intercept

BM

 8

51Cr-EDTA

Both

3

No

Med Physics

Slope–intercept

Modification

 9

99mTc-DTPA

Both

2

No

Med Physics

Slope–intercept

None

10

51Cr-EDTA

Both

3

No

Med Physics

Slope–intercept

Chantler

11

51Cr-EDTA

Peripheral

3

No

Med Physics

Slope–intercept

BM

12

51Cr-EDTA

Peripheral

2

No

Biochemistry

Slope–intercept

None

13

51Cr-EDTA

Both

2

No

Biochemistry

Slope–intercept

Chantler

14

51Cr-EDTA

Both

3

Yes

Med Physics

Slope–intercept

None

15

51Cr-EDTA

Peripheral

3

No

Med Physics

Slope–intercept

None

16

51Cr-EDTA

Both

4

No

Med Physics

Slope–intercept

BM

17

99mTc-DTPA

Both

2

No

Med Physics

Slope–intercept

BM

18

51Cr-EDTA

Both

3

Yes

Med Physics

In-house method

None

19

51Cr-EDTA

Peripheral

3

Yes

Biochemistry

Slope–intercept

None

20

51Cr-EDTA

Central

4

Yes

Med Physics

Slope–intercept

Chantler

21

51Cr-EDTA

Peripheral

3

No

Med Physics

Slope–intercept

BM

  1. BM=Brochner-Mortensen; CCLG=Children's Cancer and Leukaemia Group; GFR=glomerular filtration rate.