Table 3 Co-morbidity, symptoms at diagnosis, and route to diagnosis in the absence of symptoms by race in PROCESS cohort members; information from hospital records
Centre adjusted | Age and centre adjusted | |||||
---|---|---|---|---|---|---|
Black men n (%) | White men n (%) | Odds ratio (95% CI) | P -value | Odds ratio (95% CI) | P -value | |
Charlson co-morbidity score (n=1296) | ||||||
0 | 257 (61) | 494 (57) | ||||
1 | 96 (23) | 177 (20) | ||||
2+ | 69 (16) | 203 (23) | ||||
Odds ratio per category change | 0.95 (0.75, 1.22) | 0.71 | 1.21 (0.94, 1.57) | 0.14 | ||
Hospital records review available (n=1467) | 474 | 993 | ||||
Symptoms of metastasis? | 52 (11) | 111 (11) | 1.13 (0.78, 1.64) | 0.51 | 1.32 (0.89, 1.96) | 0.17 |
LUTS? | 301 (64) | 671 (68) | 0.95 (0.74, 1.20) | 0.66 | 1.02 (0.79, 1.31) | 0.87 |
Storage symptoms? | 232 (49) | 537 (54) | 0.96 (0.76, 1.21) | 0.71 | 1.01 (0.79, 1.29) | 0.96 |
Voiding symptoms? | 227 (48) | 537 (54) | 0.88 (0.70, 1.11) | 0.29 | 0.91 (0.71, 1.15) | 0.42 |
Acute urinary retention? | 55 (12) | 113 (11) | 1.04 (0.72, 1.49) | 0.85 | 1.40 (0.95, 2.07) | 0.093 |
Haematuria? | 34 (7) | 104 (10) | 0.67 (0.44, 1.01) | 0.056 | 0.72 (0.47, 1.12) | 0.15 |
Urinary tract infection? | 35 (7) | 62 (6) | 1.19 (0.76, 1.85) | 0.45 | 1.49 (0.92, 2.42) | 0.10 |
Chronic urinary retention? | 17 (4) | 49 (5) | 0.66 (0.37, 1.18) | 0.17 | 0.83 (0.45, 1.53) | 0.55 |
Diagnosed in the absence of symptoms | ||||||
With a PSA test | 77 (16) | 110 (11) | 1.38 (1.00, 1.92) | 0.052 | 1.26 (0.89, 1.77) | 0.19 |
With digital rectal exam | 18 (4) | 34 (3) | 1.07 (0.58, 1.96) | 0.83 | 1.07 (0.57, 2.04) | 0.83 |
With TURP | 13 (3) | 33 (3) | 1.19 (0.58, 2.46) | 0.64 | 1.59 (0.73, 3.46) | 0.25 |