Table 3 Co-morbidity, symptoms at diagnosis, and route to diagnosis in the absence of symptoms by race in PROCESS cohort members; information from hospital records

From: Pathways to diagnosis for Black men and White men found to have prostate cancer: the PROCESS cohort study

   

Centre adjusted

Age and centre adjusted

 

Black men n (%)

White men n (%)

Odds ratio (95% CI)

P -value

Odds ratio (95% CI)

P -value

Charlson co-morbidity score (n=1296)

 0

257 (61)

494 (57)

    

 1

96 (23)

177 (20)

    

 2+

69 (16)

203 (23)

    

Odds ratio per category change

  

0.95 (0.75, 1.22)

0.71

1.21 (0.94, 1.57)

0.14

Hospital records review available (n=1467)

474

993

    

 Symptoms of metastasis?

52 (11)

111 (11)

1.13 (0.78, 1.64)

0.51

1.32 (0.89, 1.96)

0.17

 LUTS?

301 (64)

671 (68)

0.95 (0.74, 1.20)

0.66

1.02 (0.79, 1.31)

0.87

 Storage symptoms?

232 (49)

537 (54)

0.96 (0.76, 1.21)

0.71

1.01 (0.79, 1.29)

0.96

 Voiding symptoms?

227 (48)

537 (54)

0.88 (0.70, 1.11)

0.29

0.91 (0.71, 1.15)

0.42

 Acute urinary retention?

55 (12)

113 (11)

1.04 (0.72, 1.49)

0.85

1.40 (0.95, 2.07)

0.093

 Haematuria?

34 (7)

104 (10)

0.67 (0.44, 1.01)

0.056

0.72 (0.47, 1.12)

0.15

 Urinary tract infection?

35 (7)

62 (6)

1.19 (0.76, 1.85)

0.45

1.49 (0.92, 2.42)

0.10

 Chronic urinary retention?

17 (4)

49 (5)

0.66 (0.37, 1.18)

0.17

0.83 (0.45, 1.53)

0.55

Diagnosed in the absence of symptoms

 With a PSA test

77 (16)

110 (11)

1.38 (1.00, 1.92)

0.052

1.26 (0.89, 1.77)

0.19

 With digital rectal exam

18 (4)

34 (3)

1.07 (0.58, 1.96)

0.83

1.07 (0.57, 2.04)

0.83

 With TURP

13 (3)

33 (3)

1.19 (0.58, 2.46)

0.64

1.59 (0.73, 3.46)

0.25

  1. LUTS=lower urinary tract symptoms; PSA=prostate-specific antigen; TURP=trans-urethral resection of the prostate.
  2. Counts are the number of men with the specified information in their hospital records.