Table 2 Human and murine matrix families conserved between Nrf2 and Nfkb1

From: Regulatory potential for concerted modulation of Nrf2- and Nfkb1-mediated gene expression in inflammation and carcinogenesis

Matrix family (Human NRF2 vs NFKB1)

Matrix family (Murine Nrf2 vs Nfkb1)

Matrix family conserved after multiple species alignment (NRF2 vs NFKB1)

Family information

V$AHRR

AHR-arnt heterodimers and AHR-related factors

V$AIRE

Autoimmune regulatory element-binding factor

V$AP1R

MAF- and AP1-related factors

V$AP2F

Activator protein 2

V$AP4R

V$AP4R

Activator protein 4 and related proteins

V$ATBF

AT-binding transcription factor

V$BCL6

V$BCL6

POZ domain zinc finger expressed in B-cells

V$BRAC

Brachyury gene, mesoderm developmental factor

V$BRNF

Brn POU domain factors

V$CAAT

CCAAT-binding factors

V$CART

Cart-1 (cartilage homoeoprotein 1)

V$CDXF

Vertebrate caudal related homoeodomain protein

V$CEBP

Ccaat/enhancer-binding protein

V$CHRF

V$CHRF

Cell cycle regulators: cell cycle homology element

V$CIZF

CAS-interating zinc finger protein

V$CLOX

CLOX and CLOX homology (CDP) factors

V$COMP

Factors that cooperate with myogenic proteins

V$CREB

V$CREB

Camp-responsive element-binding proteins

V$CTCF

CTCF and BORIS gene family, transcriptional regulators with 11 highly conserved zinc finger domains

V$E2FF

V$E2FF

E2F-myc activator/cell cycle regulator

V$E4FF

Ubiquitous GLI-krueppel-like zinc finger involved in cell cycle regulation

V$EBOX

V$EBOX

E-box-binding factors

V$EGRF

EGR/nerve growth factor-induced protein C and related factors

V$EKLF

V$EKLF

V$EKLF

Basic and erythroid krueppel-like factors

V$EREF

Estrogen response elements

V$ETSF

V$ETSF

Human and murine ETS1 factors

V$EVI1

EVI1 myeloid-transforming protein

V$FKHD

V$FKHD

Fork head domain factors

V$FXRE

Farnesoid X-activated receptor response elements

V$GATA

V$GATA

V$GATA

GATA-binding factors

V$GFI1

V$GFI1

Growth factor independence transcriptional repressor

V$GREF

Glucocorticoid responsive and related elements

V$GRHL

Grainyhead-like transcription factors

V$HAND

bHLH transcription factor dimer of HAND2 and E12

V$HEAT

V$HEAT

Heat-shock factors

V$HESF

Vertebrate homologues of enhancer of split complex

V$HNF1

Hepatic nuclear factor 1

V$HNF6

Onecut homoeodomain factor HNF6

V$HOMF

Homoeodomain transcription factors

V$HOXC

HOX–PBX complexes

V$HOXF

V$HOXF

V$HOXF

Factors with moderate activity to homoeodomain consensus sequence

V$IKRS

Ikaros zinc finger family

V$IRFF

Interferon regulatory factors

V$LEFF

V$LEFF

LEF1/TCF, involved in the Wnt signal transduction pathway

V$LHXF

Lim homoeodomain factors

V$MAZF

V$MAZF

Myc-associated zinc fingers

V$MEF2

MEF2, myocyte-specific enhancer-binding factor

V$MYBL

Cellular and viral myb-like transcriptional regulators

V$MYOD

V$MYOD

Myoblast-determining factors

V$MYT1

MYT1 C2HC zinc finger protein

V$MZF1

Myeloid zinc finger 1 factors

V$NEUR

V$NEUR

NeuroD, β2, HLH domain

V$NF1F

Nuclear factor 1

V$NFAT

Nuclear factor of activated T cells

V$NFKB

Nuclear factor κ B/c-rel

V$NKX6

NK6 homoeobox transcription factors

V$NKXH

NKX homoeodomain factors

V$NR2F

V$NR2F

V$NR2F

Nuclear receptor subfamily 2 factors

V$NRF1

Nuclear respiratory factor 1

V$OCT1

Octamer-binding protein

V$OCTP

OCT1-binding factor (POU-specific domain)

V$P53F

V$P53F

p53 tumour suppressor

V$PARF

PAR/bZIP family

V$PAX5

PAX-5 B cell-specific activator protein

V$PAX6

V$PAX6

PAX-4/PAX-6 paired domain-binding sites

V$PBXC

PBX1–MEIS1 complexes

V$PDX1

Pancreatic and intestinal homoeodomain transcription factor

V$PERO

Peroxisome proliferator-activated receptor

V$PIT1

GHF-1 pituitary-specific pou domain transcription factor

V$PLAG

Pleomorphic adenoma gene

V$PLZF

V$PLZF

C2H2 zinc finger protein PLZF

V$PRDF

Positive regulatory domain I-binding factor

V$PTF1

Pancreas transcription factor 1, heterotrimeric transcription factor

V$RBIT

Regulator of B-cell IgH transcription

V$RUSH

SWI/SNF-related nucleophosphoproteins with a RING finger DNA-binding motif

V$RXRF

V$RXRF

V$RXRF

RXR heterodimer-binding sites

V$SATB

Special AT-rich sequence-binding protein

V$SF1F

V$SF1F

Vertebrate steroidogenic factor

V$SMAD

Vertebrate SMAD family of transcription factors

V$SNAP

snRNA-activating protein complex

V$SORY

V$SORY

V$SORY

SOX/SRY-sex/testis-determining and related HMG box factors

V$SP1F

V$SP1F

V$SP1F

GC-Box factors SP1/GC

V$SRFF

V$SRFF

Serum response element-binding factor

V$STAT

V$STAT

Signal transducer and activator of transcription

V$TALE

TALE homoeodomain class-recognising TG motifs

V$TBPF

V$TBPF

Tata-binding protein factor

V$WHNF

Winged helix-binding sites

V$XBBF

X-box-binding factors

V$ZBPF

V$ZBPF

Zinc-binding protein factors

V$ZF35

Zinc finger protein ZNF35

V$ZFHX

V$ZFHX

Two-handed zinc finger homoeodomain transcription factors