Table 1 FOLFOX (5-fluorouracil (5FU), folinic acid and oxaliplatin) dose levels
Dose level a | Oxaliplatin X mg m −2 | Bolus 5FU Y mg m −2 day −1 | Continuous infusion 5FU Z mg m −2 day −1 |
|---|---|---|---|
1 | 50 | 300 | 400 |
2 | 50 | 400 | 600 |
3 | 75 | 400 | 600 |
4 | 85 | 400 | 600 |
5 | 100 | 400 | 600 |
Dose level a | Oxaliplatin X mg m −2 | Bolus 5FU Y mg m −2 day −1 | Continuous infusion 5FU Z mg m −2 day −1 |
|---|---|---|---|
1 | 50 | 300 | 400 |
2 | 50 | 400 | 600 |
3 | 75 | 400 | 600 |
4 | 85 | 400 | 600 |
5 | 100 | 400 | 600 |
