Figure 1
From: Polyoma virus infection and urothelial carcinoma of the bladder following renal transplantation
Tumour tissue from patient 7, showing high-grade invasive urothelial carcinoma (A), with focal squamous differentiation (B). High power (C) reveals no evidence of typical viral inclusions on H&E stain. Immunohistochemistry for PV T-Ag is negative in non-neoplastic urothelium adjacent to the tumour (D), but shows intense nuclear staining in almost all tumour cells (E and F).
