Table 1 Analysis of function of differentially expressed genes
From: A genome-wide expression analysis identifies a network of EpCAM-induced cell cycle regulators
Number of differentially expressed genes (induced/repressed) | ||||||
---|---|---|---|---|---|---|
(A) Functional category | A2C12 | A549 | Caco-2 | A2C12/A549 a | ||
Cell cycleb | 232 (126/106) | 153 (73/80) | 33 (25/8) | 29 (20/9) | ||
Cellular growth and proliferationc | 415 (204/211) | 306 (139/167) | 46 (33/13) | 48 (29/19) | ||
Cell deathd | 395 (202/193) | 265 (128/137) | 62 (48/14) | 49 (33/16) | ||
Cancere | 462 (242/220) | 344 (155/189) | 77 (54/23) | 54 (31/23) | ||
Number of differentially expressed genes (induced/repressed) | ||||||
(B) Cell cycle phase | A2C12 | A549 | Caco-2 | A2C12/A549/Caco-2 a | A2C12/A549 a | A549/Caco-2 a |
G0/G1 phases and G1/S transition | 58 (25/33) | 38 (20/18) | 8 (5/3) | 2 (2/0) | 9 (6/3) | 3 (2/1) |
S phase | 36 (21/15) | 28 (16/12) | 1 (0/1) | 1 (1/0) | 4 (3/0) | 1 (0/1) |
G2/M phases | 38 (27/11) | 18 (12/6) | 5 (4/1) | 3 (3/0) | 4 (4/0) | 0 |