Figure 2
(A) PRL-3 normalised expression for 80 primary tumours adjusted for their counterpart normal mucoses. As values did not fit a normal distribution (Kolmogorov–Smirnov test P<0.0001), extremely high values plotted to the right of the dashed line were coded as ‘high expression’. Values on the left of the dashed line (72 patients) were evaluated to fit a normal distribution (Kolmogorov–Smirnov test P=0.113); therefore, in (B), we plotted values of PRL-3 expression for the normally distributed values. Dashed line designates the median value (cutoff) and separates two populations coded as ‘low expression’ and ‘high expression’. Then, 38 values were coded as high expression and 42 values as low expression.
