Figure 6

Kaplan–Meier survival analysis. Survival of mice with established brain tumours derived from U87 glioblastoma cells injected intracranially with 50 mg kg⁻¹ of LLL-3 three days after implantation (n=5). Control mice with established brain tumours derived from U87 glioblastoma cells received no treatment (untreated control (n=5)). Survival was measured from the day of intracranial implantation of U87 glioblastoma cells. The median survival time of untreated control and DMSO vehicle-treated mice were 17.5 and 16 days, respectively whereas the LLL-3-treated mices’ survival was significantly increased to 28.5 days. The log-rank test was used to assess the statistical differences in survival among the two groups; P=0.03.