Table 2 Univariate and multivariate analysis for distant metastasis (logistic regression model)
 | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
 | RR | 95% CI | P -value | RR | 96% CI | P -value |
Histological grade (Differentiated/undifferentiated) | 2.35 | 1.31–2.35 | <0.0001 | 0.58 | 0.24–1.45 | 0.239 |
pT (Depth of tumour invasion) | 49.91 | 27.36–99.07 | <0.0001 | 28.17 | 14.30–60.95 | <0.0001 |
pN (Lymph node metastasis) | 22.78 | 11.56–51.49 | <0.0001 | 6.5 | 2.99–15.77 | <0.0001 |
Lymphatic invasion | 12.12 | 6.89–23.12 | <0.0001 | — | — | — |
Venous invasion | 4.55 | 2.91–7.10 | <0.0001 | 1.61 | 0.90–2.88 | 0.106 |
uPAR mRNA expression in bone marrow | 1.53 | 1.01–2.35 | 0.046 | — | — | — |
uPAR mRNA expression in peripheral blood | 1.95 | 1.28–2.99 | 0.002 | 1.85 | 1.08–3.23 | 0.0207 |