Table 4 Plasmatic levels of total and free VPA

From: A phase I–II study of the histone deacetylase inhibitor valproic acid plus chemoimmunotherapy in patients with advanced melanoma

Total VPA plasmatic levels (mg l−1)

No. of patients

0–50

0

51–100

8

101–150

14

151–200

5

Free VPA plasmatic levels (mg l−1)

No. of patients

10

4

10.1–20

7

20.1–30

4

30.1–40

7

40.1–50

2

50.1–60

3

  1. Abbreviation: VPA=valproic acid.