Table 2 Standardised incidence ratios (SIRs) of breast cancer by age group

From: Breast cancer risks in women with a family history of breast or ovarian cancer who have tested negative for a BRCA1 or BRCA2 mutation

Age group

Observed (rate per 105)

Expected (rate per 105)

SIRs

95% CI

P -value

25–39

11 (42.9)

0.74 (2.9)

14.9

8.30–26.6

<0.0001

40–49

12 (50.0)

3.29 (13.7)

3.64

2.09–6.38

0.001

50–59

17 (97.7)

4.02 (23.1)

4.23

2.64–6.77

<0.0001

60 and above

25 (103.9)

8.44 (35.1)

2.96

2.01–4.37

<0.0001

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